KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
21.21
Human Site:
T137
Identified Species:
33.33
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
T137
I
V
R
N
A
K
D
T
A
H
T
K
A
E
R
Chimpanzee
Pan troglodytes
XP_523815
451
50966
V105
G
K
G
G
Y
G
K
V
F
Q
V
R
K
V
T
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
G137
L
I
K
K
C
R
D
G
L
H
L
K
K
E
K
Dog
Lupus familis
XP_537702
525
59107
T137
I
V
R
N
A
K
D
T
A
H
T
K
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
T137
I
V
R
N
A
K
D
T
A
H
T
K
A
E
R
Rat
Rattus norvegicus
P67999
525
59113
T137
I
V
R
N
A
K
D
T
A
H
T
K
A
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
E106
A
E
R
N
I
L
E
E
V
K
H
P
F
I
V
Chicken
Gallus gallus
P18652
752
84421
R124
A
T
L
K
V
R
D
R
V
R
T
K
I
E
R
Frog
Xenopus laevis
P10666
629
71268
T109
K
V
R
D
R
V
R
T
K
M
E
R
D
I
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
R111
A
S
L
K
V
R
D
R
V
R
T
K
M
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
A307
V
V
Q
K
R
K
T
A
E
H
T
K
T
E
R
Honey Bee
Apis mellifera
XP_395876
456
51514
I109
V
L
R
K
A
S
I
I
R
N
Q
K
D
T
A
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
R148
A
T
L
K
V
R
D
R
Q
R
T
K
L
E
R
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T118
I
V
R
N
Q
K
D
T
A
H
T
K
A
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S117
I
K
E
N
D
E
F
S
G
N
D
D
T
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
0
26.6
100
N.A.
100
100
N.A.
13.3
33.3
20
33.3
N.A.
46.6
20
33.3
93.3
P-Site Similarity:
100
6.6
60
100
N.A.
100
100
N.A.
20
40
33.3
40
N.A.
60
40
40
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
0
34
0
0
7
34
0
0
0
34
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
60
0
0
0
7
7
14
7
0
% D
% Glu:
0
7
7
0
0
7
7
7
7
0
7
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
0
7
0
0
% F
% Gly:
7
0
7
7
0
7
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
47
7
0
0
0
0
% H
% Ile:
40
7
0
0
7
0
7
7
0
0
0
0
7
14
0
% I
% Lys:
7
14
7
40
0
40
7
0
7
7
0
74
14
0
7
% K
% Leu:
7
7
20
0
0
7
0
0
7
0
7
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
0
0
0
47
0
0
0
0
0
14
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
0
7
7
7
0
0
0
0
% Q
% Arg:
0
0
54
0
14
27
7
20
7
20
0
14
0
0
60
% R
% Ser:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
7
% S
% Thr:
0
14
0
0
0
0
7
40
0
0
60
0
14
7
7
% T
% Val:
14
47
0
0
20
7
0
7
20
0
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _